{"id":112198,"date":"2026-06-17T16:37:01","date_gmt":"2026-06-17T12:07:01","guid":{"rendered":"https:\/\/medpip.com\/mag\/?p=112198"},"modified":"2026-06-17T16:37:01","modified_gmt":"2026-06-17T12:07:01","slug":"hematology-case-studies-4","status":"publish","type":"post","link":"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/","title":{"rendered":"\u0622\u0632\u0645\u0648\u0646\u200c\u0647\u0627\u06cc \u0645\u0635\u0648\u0631 \u062a\u0634\u062e\u06cc\u0635\u06cc \u062f\u0631 \u0647\u0645\u0627\u062a\u0648\u0644\u0648\u0698\u06cc (\u0633\u0631\u06cc \u0686\u0647\u0627\u0631\u0645)"},"content":{"rendered":"
[vc_row][vc_column][vc_column_text css=””]\n

\u0633\u0624\u0627\u0644 31<\/span><\/h2>\n[\/vc_column_text][vc_column_text css=””]\n

\u062a\u0635\u0648\u06cc\u0631 31 \u0622\u0633\u067e\u06cc\u0631\u0627\u0633\u06cc\u0648\u0646 \u0645\u063a\u0632 \u0627\u0633\u062a\u062e\u0648\u0627\u0646 \u0627\u0632 \u06cc\u06a9 \u067e\u0633\u0631 \u06f1\u06f6 \u0633\u0627\u0644\u0647 \u0631\u0627 \u0646\u0634\u0627\u0646 \u0645\u06cc\u200c\u062f\u0647\u062f \u06a9\u0647 \u0645\u0634\u062e\u0635 \u0634\u062f \u062f\u0686\u0627\u0631 \u0644\u0646\u0641\u0627\u062f\u0646\u0648\u067e\u0627\u062a\u06cc (lymphadenopathy) \u0634\u062f\u0647 \u0627\u0633\u062a. \u062a\u0634\u062e\u06cc\u0635 \u0686\u06cc\u0633\u062a\u061f<\/span><\/p>\n[\/vc_column_text][vc_single_image image=”112372″ img_size=”full” css=””][vc_column_text css=””]\u067e\u0627\u0633\u062e <\/strong><\/span><\/p>\n

\u0627\u06cc\u0646 \u062a\u0635\u0648\u06cc\u0631 \u0646\u0634\u0627\u0646\u200c\u062f\u0647\u0646\u062f\u0647 \u0645\u063a\u0632 \u0627\u0633\u062a\u062e\u0648\u0627\u0646\u06cc \u0627\u0633\u062a \u06a9\u0647 \u0627\u0632 \u0633\u0644\u0648\u0644\u200c\u0647\u0627\u06cc \u0628\u0644\u0627\u0633\u062a (blast cells) \u062a\u0634\u06a9\u06cc\u0644 \u0634\u062f\u0647 \u0627\u0633\u062a \u06a9\u0647 \u062f\u0627\u0631\u0627\u06cc \u0646\u0633\u0628\u062a \u0647\u0633\u062a\u0647 \u0628\u0647 \u0633\u06cc\u062a\u0648\u067e\u0644\u0627\u0633\u0645 \u0628\u0627\u0644\u0627 \u0647\u0633\u062a\u0646\u062f.\u062f\u0631 \u0628\u0631\u062e\u06cc \u0627\u0632 \u0627\u06cc\u0646 \u0633\u0644\u0648\u0644\u200c\u0647\u0627\u060c \u06a9\u0631\u0648\u0645\u0627\u062a\u06cc\u0646 \u0647\u0633\u062a\u0647\u200c\u0627\u06cc (nuclear chromatin) \u0628\u0647 \u0635\u0648\u0631\u062a \u062a\u062c\u0645\u0639\u200c\u06cc\u0627\u0641\u062a\u0647 (clumped) \u062f\u06cc\u062f\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f\u060c \u062f\u0631 \u062d\u0627\u0644\u06cc \u06a9\u0647 \u062f\u0631 \u0628\u0631\u062e\u06cc \u062f\u06cc\u06af\u0631 \u0648\u0627\u06a9\u0648\u0626\u0644\u0647 \u0634\u062f\u0646 (vacuolation) \u0645\u0634\u0627\u0647\u062f\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f. \u0645\u0642\u062f\u0627\u0631\u06cc \u062a\u0646\u0648\u0639 \u062f\u0631 \u0627\u0646\u062f\u0627\u0632\u0647 \u0633\u0644\u0648\u0644\u200c\u0647\u0627\u00a0 \u0648\u062c\u0648\u062f \u062f\u0627\u0631\u062f \u0648 \u0646\u0633\u0628\u062a \u0628\u06cc\u0634\u062a\u0631\u06cc \u0627\u0632 \u0633\u0644\u0648\u0644\u200c\u0647\u0627\u06cc \u0628\u0632\u0631\u06af\u200c\u062a\u0631 \u062f\u06cc\u062f\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f. \u0628\u0631\u062e\u06cc \u0627\u0632 \u0633\u0644\u0648\u0644\u200c\u0647\u0627 \u062f\u0627\u0631\u0627\u06cc \u0646\u0648\u06a9\u0644\u0626\u0648\u0644\u200c\u0647\u0627\u06cc \u0628\u0631\u062c\u0633\u062a\u0647 (prominent nucleoli) \u0647\u0633\u062a\u0646\u062f. \u062a\u0634\u062e\u06cc\u0635 \u0644\u0648\u0633\u0645\u06cc \u0644\u0646\u0641\u0648\u0628\u0644\u0627\u0633\u062a\u06cc\u06a9 \u062d\u0627\u062f (acute lymphoblastic leukaemia \u2013 ALL) \u0627\u0632 \u0632\u06cc\u0631\u06af\u0631\u0648\u0647 FAB \u0646\u0648\u0639 L2.\u0627\u0633\u062a. \u0627\u06cc\u0646 \u0632\u06cc\u0631\u06af\u0631\u0648\u0647 \u062f\u0631 \u06af\u0631\u0648\u0647\u200c\u0647\u0627\u06cc \u0633\u0646\u06cc \u0628\u0627\u0644\u0627\u062a\u0631\u00a0 \u0634\u0627\u06cc\u0639\u200c\u062a\u0631 \u0627\u0633\u062a \u0648 \u0628\u0631\u062e\u06cc \u0645\u0637\u0627\u0644\u0639\u0627\u062a \u0646\u0634\u0627\u0646 \u062f\u0627\u062f\u0647\u200c\u0627\u0646\u062f \u06a9\u0647 \u0646\u0633\u0628\u062a \u0628\u0647 \u0633\u0627\u06cc\u0631 \u0632\u06cc\u0631\u06af\u0631\u0648\u0647\u200c\u0647\u0627\u06cc FAB \u062f\u0627\u0631\u0627\u06cc \u067e\u06cc\u0634 \u0622\u06af\u0647\u06cc \u0636\u0639\u06cc\u0641 \u062a\u0631\u0627\u0633\u062a.<\/span><\/p>\n

\u0639\u0648\u0627\u0645\u0644 \u0645\u0639\u0645\u0648\u0644 \u062a\u0639\u06cc\u06cc\u0646\u200c\u06a9\u0646\u0646\u062f\u0647 \u067e\u06cc\u0634\u200c\u0622\u06af\u0647\u06cc \u0639\u0628\u0627\u0631\u062a\u200c\u0627\u0646\u062f \u0627\u0632:<\/span><\/p>\n

    \n
  • \u0633\u0646<\/span><\/li>\n
  • \u062a\u0639\u062f\u0627\u062f \u06af\u0644\u0628\u0648\u0644 \u0633\u0641\u06cc\u062f \u0647\u0646\u06af\u0627\u0645 \u0645\u0631\u0627\u062c\u0639\u0647<\/span><\/li>\n
  • \u062c\u0646\u0633\u06cc\u062a<\/span><\/li>\n<\/ul>\n[\/vc_column_text][vc_separator color=”blue” border_width=”2″ css=””][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css=””]\n

    \u0633\u0624\u0627\u0644 32<\/span><\/h2>\n[\/vc_column_text][vc_column_text css=””]\n

    \u0634\u06a9\u0644 32 \u0631\u0627\u062f\u06cc\u0648\u06af\u0631\u0627\u0641\u06cc \u0642\u0641\u0633\u0647 \u0633\u06cc\u0646\u0647\u00a0 \u0627\u0632 \u06cc\u06a9 \u0645\u0631\u062f \u06f4\u06f8 \u0633\u0627\u0644\u0647 \u0627\u0633\u062a \u06a9\u0647 \u062a\u062d\u062a \u0634\u06cc\u0645\u06cc\u200c\u062f\u0631\u0645\u0627\u0646\u06cc \u0634\u062f\u06cc\u062f \u0628\u0631\u0627\u06cc \u0644\u0646\u0641\u0648\u0645 \u063a\u06cc\u0631\u0647\u0648\u0686\u06a9\u06cc\u0646 \u0642\u0631\u0627\u0631 \u062f\u0627\u0631\u062f.\u0627\u0648 \u0628\u0647 \u0645\u062f\u062a \u062f\u0648 \u0647\u0641\u062a\u0647 \u062f\u0686\u0627\u0631 \u0646\u0648\u062a\u0631\u0648\u067e\u0646\u06cc \u0648 \u062a\u0628\u200c \u0628\u0648\u062f\u0647 \u0648 \u0686\u0646\u062f\u06cc\u0646 \u062a\u0631\u06a9\u06cc\u0628 \u0645\u062e\u062a\u0644\u0641 \u0627\u0632 \u0622\u0646\u062a\u06cc\u200c\u0628\u06cc\u0648\u062a\u06cc\u06a9\u200c\u0647\u0627\u06cc \u0648\u0633\u06cc\u0639\u200c\u0627\u0644\u0637\u06cc\u0641 \u062f\u0631\u06cc\u0627\u0641\u062a \u06a9\u0631\u062f\u0647 \u0627\u0633\u062a.\u0627\u06cc\u0646 \u0631\u0627\u062f\u06cc\u0648\u06af\u0631\u0627\u0641\u06cc \u0686\u0647 \u0686\u06cc\u0632\u06cc \u0631\u0627 \u0646\u0634\u0627\u0646 \u0645\u06cc\u200c\u062f\u0647\u062f \u0648 \u062a\u0634\u062e\u06cc\u0635 \u0627\u062d\u062a\u0645\u0627\u0644\u06cc \u0686\u06cc\u0633\u062a\u061f<\/span><\/p>\n[\/vc_column_text][vc_single_image image=”112374″ img_size=”full” css=””][vc_column_text css=””]\n

    \u067e\u0627\u0633\u062e<\/strong><\/span><\/p>\n

    \u0631\u0627\u062f\u06cc\u0648\u06af\u0631\u0627\u0641\u06cc \u0642\u0641\u0633\u0647 \u0633\u06cc\u0646\u0647 \u062a\u0639\u062f\u0627\u062f\u06cc \u06a9\u062f\u0648\u0631\u062a (opacities) \u0631\u0627 \u0646\u0634\u0627\u0646 \u0645\u06cc\u200c\u062f\u0647\u062f\u060c \u0628\u0647\u200c\u0648\u06cc\u0698\u0647 \u062f\u0631 \u0645\u06cc\u062f\u0627\u0646\u200c\u0647\u0627\u06cc \u0631\u06cc\u0647 \u0686\u067e.<\/span><\/p>\n

    \u0627\u06cc\u0646 \u06a9\u062f\u0648\u0631\u062a\u200c\u0647\u0627 \u06af\u0631\u062f \u0647\u0633\u062a\u0646\u062f \u0648 \u062f\u0631 \u0627\u06cc\u0646 \u0634\u0631\u0627\u06cc\u0637 \u062a\u06cc\u067e\u06cc\u06a9 \u0622\u0633\u067e\u0631\u0698\u06cc\u0644\u0648\u0645\u0627\u0645\u062d\u0633\u0648\u0628 \u0645\u06cc\u200c\u0634\u0648\u0646\u062f.<\/span><\/p>\n

    \u062f\u0631 \u0648\u0627\u0642\u0639 \u0627\u06cc\u0646 \u062a\u0634\u062e\u06cc\u0635 \u0628\u0627 \u0628\u0631\u0648\u0646\u06a9\u0648\u0633\u06a9\u0648\u067e\u06cc \u062a\u0623\u06cc\u06cc\u062f \u0648 \u062f\u0631\u0645\u0627\u0646 \u0628\u0627 \u0622\u0645\u0641\u0648\u062a\u0631\u06cc\u0633\u06cc\u0646 \u062f\u0627\u062e\u0644\u200c\u0648\u0631\u06cc\u062f\u06cc \u0627\u0646\u062c\u0627\u0645 \u0645\u06cc\u200c\u0634\u0648\u062f.<\/span><\/p>\n[\/vc_column_text][vc_separator color=”blue” border_width=”2″ css=””][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css=””]\n

    \u0633\u0624\u0627\u0644 33<\/span><\/h2>\n[\/vc_column_text][vc_single_image image=”112376″ img_size=”full” css=””][vc_column_text css=””]\n

    \u062a\u0635\u0648\u06cc\u0631 33 \u06af\u0633\u062a\u0631\u0634 \u062e\u0648\u0646 \u0645\u062d\u06cc\u0637\u06cc \u0627\u0632 \u06cc\u06a9 \u0628\u0627\u0646\u0648\u06cc \u0645\u06cc\u0627\u0646\u200c\u0633\u0627\u0644 \u0627\u0633\u062a .\u0627\u06cc\u0646 \u0644\u0627\u0645 \u0686\u0647 \u0686\u06cc\u0632\u06cc \u0631\u0627 \u0646\u0634\u0627\u0646 \u0645\u06cc\u200c\u062f\u0647\u062f\u061f<\/span><\/p>\n[\/vc_column_text][vc_column_text css=””]\n

    \u067e\u0627\u0633\u062e<\/strong><\/span><\/p>\n

    \u062f\u0631 \u0627\u06cc\u0646 \u062a\u0635\u0648\u06cc\u0631 \u06af\u0644\u0628\u0648\u0644\u200c\u0647\u0627\u06cc \u0642\u0631\u0645\u0632\u060c \u0645\u0627\u06a9\u0631\u0648\u0633\u06cc\u062a\u06cc\u06a9 (macrocytic) \u0648 \u0639\u0645\u062f\u062a\u0627\u064b \u06af\u0631\u062f (round) \u0647\u0633\u062a\u0646\u062f. \u0686\u0646\u062f \u0633\u0644\u0648\u0644 \u062a\u0627\u0631\u06af\u062a (target cells) \u0646\u06cc\u0632 \u062f\u06cc\u062f\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f.\u0644\u0646\u0641\u0648\u0633\u06cc\u062a \u06a9\u0648\u0686\u06a9 (small lymphocyte) \u0627\u06cc\u062f\u0647\u200c\u0627\u06cc \u0627\u0632 \u0642\u0637\u0631 \u06af\u0644\u0628\u0648\u0644 \u0642\u0631\u0645\u0632 \u0628\u0647\u200c\u062f\u0633\u062a \u0645\u06cc\u200c\u062f\u0647\u062f\u061b \u0628\u0647\u200c\u0637\u0648\u0631\u06cc \u06a9\u0647 \u0628\u06cc\u0634\u062a\u0631 \u0627\u0631\u06cc\u062a\u0631\u0648\u0633\u06cc\u062a\u200c\u0647\u0627 (erythrocytes) \u0628\u0632\u0631\u06af\u200c\u062a\u0631 \u0627\u0632 \u0642\u0637\u0631 \u0647\u0633\u062a\u0647 \u00a0\u0644\u0646\u0641\u0648\u0633\u06cc\u062a (lymphocyte nucleus) \u0647\u0633\u062a\u0646\u062f.<\/span><\/p>\n

    \u0646\u0648\u062a\u0631\u0648\u0641\u06cc\u0644 \u0647\u0627\u06cc\u067e\u0631\u0633\u06af\u0645\u0646\u062a\u200c\u0634\u062f\u0647 \u0646\u06cc\u0633\u062a (not hypersegmented) \u0648 \u0627\u06cc\u0646 \u0645\u0648\u0636\u0648\u0639 \u0646\u0634\u0627\u0646 \u0645\u06cc\u200c\u062f\u0647\u062f \u06a9\u0647 \u0639\u0644\u062a \u0632\u0645\u06cc\u0646\u0647\u200c\u0627\u06cc \u0627\u062d\u062a\u0645\u0627\u0644\u0627\u064b \u0645\u0648\u0627\u0631\u062f \u0632\u06cc\u0631 \u0627\u0633\u062a\u060c \u0646\u0647 \u06a9\u0645\u0628\u0648\u062f B12 \u06cc\u0627 \u0641\u0648\u0644\u0627\u062a (B12 or folate deficiency).<\/span><\/p>\n

      \n
    • \u0628\u06cc\u0645\u0627\u0631\u06cc \u06a9\u0628\u062f\u06cc (liver disease)<\/span><\/li>\n
    • \u0647\u06cc\u067e\u0648\u062a\u06cc\u0631\u0648\u0626\u06cc\u062f\u06cc (hypothyroidism)<\/span><\/li>\n
    • \u06cc\u0627 \u0645\u0635\u0631\u0641 \u0627\u0644\u06a9\u0644 (alcohol)<\/span><\/li>\n<\/ul>\n

      \u0627\u0646\u062f\u0627\u0632\u0647 \u0633\u0644\u0648\u0644 \u062f\u0631 \u0644\u0627\u0645 \u062e\u0648\u0646 \u0645\u062d\u06cc\u0637\u06cc (peripheral blood film) \u062a\u0639\u06cc\u06cc\u0646\u200c\u06a9\u0631\u062f\u0646\u06cc \u0646\u06cc\u0633\u062a\u060c \u0627\u06af\u0631\u0686\u0647 \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0627\u0632 \u0647\u0633\u062a\u0647 \u0644\u0646\u0641\u0648\u0633\u06cc\u062a \u0628\u0631\u0627\u06cc \u0633\u0646\u062c\u0634 \u0627\u0646\u062f\u0627\u0632\u0647 \u0645\u06cc\u200c\u062a\u0648\u0627\u0646\u062f \u0645\u0641\u06cc\u062f \u0628\u0627\u0634\u062f.<\/span><\/p>\n

      \u0628\u0627 \u0627\u06cc\u0646 \u062d\u0627\u0644\u060c \u0628\u06cc\u0634\u062a\u0631\u06cc\u0646 \u0627\u062a\u06a9\u0627 \u0628\u0627\u06cc\u062f \u0628\u0647 \u062d\u062c\u0645 \u0645\u062a\u0648\u0633\u0637 \u06af\u0644\u0628\u0648\u0644 \u0642\u0631\u0645\u0632 (mean cell volume \u2013 MCV) \u0628\u0627\u0634\u062f \u06a9\u0647 \u062a\u0648\u0633\u0637 \u0634\u0645\u0627\u0631\u0634\u06af\u0631\u0647\u0627\u06cc \u0627\u0644\u06a9\u062a\u0631\u0648\u0646\u06cc\u06a9\u06cc \u0645\u062f\u0631\u0646 (modern electronic counters) \u0627\u0646\u062f\u0627\u0632\u0647\u200c\u06af\u06cc\u0631\u06cc \u0645\u06cc\u200c\u0634\u0648\u062f.<\/span><\/p>\n[\/vc_column_text][vc_separator color=”blue” border_width=”2″ css=””][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css=””]\n

      \u0633\u0624\u0627\u0644 34<\/span><\/h2>\n[\/vc_column_text][vc_column_text css=””]\n

      \u0634\u06a9\u0644 34 \u06af\u0633\u062a\u0631\u0634 \u062e\u0648\u0646 \u0645\u062d\u06cc\u0637\u06cc \u0627\u0632 \u06cc\u06a9 \u0645\u0631\u062f \u06f3\u06f4 \u0633\u0627\u0644\u0647 \u06a9\u0647 \u0628\u0647 \u0627\u0648\u0631\u0698\u0627\u0646\u0633 \u0645\u0631\u0627\u062c\u0639\u0647 \u06a9\u0631\u062f\u0647 \u0627\u0633\u062a \u0631\u0627 \u0646\u0634\u0627\u0646 \u0645\u06cc\u200c\u062f\u0647\u062f. \u062f\u0631 \u0645\u0639\u0627\u06cc\u0646\u0647 \u06cc\u06a9 \u0627\u0633\u06a9\u0627\u0631 \u0634\u06a9\u0645\u06cc (abdominal scar) \u0645\u0634\u0627\u0647\u062f\u0647 \u0634\u062f. \u0686\u0647 \u0646\u0627\u0647\u0646\u062c\u0627\u0631\u06cc\u200c\u0647\u0627\u06cc\u06cc \u062f\u06cc\u062f\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f\u061f<\/span><\/p>\n[\/vc_column_text][vc_single_image image=”112378″ img_size=”full” css=””][vc_column_text css=””]\n

      \u067e\u0627\u0633\u062e\u00a0<\/span><\/strong><\/p>\n

      \u0622\u0646\u06cc\u0632\u0648\u0633\u06cc\u062a\u0648\u0632 (anisocytosis) \u0628\u0647\u200c\u0645\u0639\u0646\u06cc \u062a\u063a\u06cc\u06cc\u0631 \u0627\u0646\u062f\u0627\u0632\u0647 \u00a0\u06af\u0644\u0628\u0648\u0644\u200c\u0647\u0627\u06cc \u0642\u0631\u0645\u0632 \u0648 \u0686\u0646\u062f \u0633\u0644\u0648\u0644 \u062a\u0627\u0631\u06af\u062a (target cells) \u062f\u06cc\u062f\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f.<\/span><\/p>\n

      \u0686\u0646\u062f \u0627\u06cc\u0646\u0648\u0698\u0646 \u0628\u0627\u0632\u0648\u0641\u06cc\u0644\u06cc\u06a9 (basophilic inclusions) \u0646\u06cc\u0632 \u062f\u0631 \u062f\u0627\u062e\u0644 \u06af\u0644\u0628\u0648\u0644\u200c\u0647\u0627\u06cc \u0642\u0631\u0645\u0632 \u0645\u0634\u0627\u0647\u062f\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f\u061b \u06cc\u06a9\u06cc \u0627\u0632 \u0622\u0646\u200c\u0647\u0627 \u062f\u0648 \u0627\u0646\u06a9\u0644\u0648\u0632\u06cc\u0648\u0646 (two inclusion bodies) \u062f\u0627\u0631\u062f.<\/span><\/p>\n

      \u0627\u06cc\u0646 \u0648\u0636\u0639\u06cc\u062a \u0645\u0639\u0645\u0648\u0644\u0627\u064b \u067e\u0633 \u0627\u0632 \u0627\u0633\u067e\u0644\u0646\u06a9\u062a\u0648\u0645\u06cc (following splenectomy) \u0631\u062e \u0645\u06cc\u200c\u062f\u0647\u062f (\u06a9\u0647 \u0645\u0645\u06a9\u0646 \u0627\u0633\u062a \u0628\u0647 \u062f\u0644\u0627\u06cc\u0644 \u0645\u062e\u062a\u0644\u0641 \u0627\u0646\u062c\u0627\u0645 \u0634\u062f\u0647 \u0628\u0627\u0634\u062f).<\/span><\/p>\n

      \u0639\u0644\u0627\u0648\u0647 \u0628\u0631 \u0627\u06cc\u0646\u060c \u0645\u06cc\u06a9\u0631\u0648\u0633\u0641\u0631\u0648\u0633\u06cc\u062a\u200c\u0647\u0627 (microspherocytes) \u0646\u06cc\u0632 \u0627\u063a\u0644\u0628 \u062f\u0631 \u0627\u06cc\u0646 \u0634\u0631\u0627\u06cc\u0637 \u062f\u06cc\u062f\u0647 \u0645\u06cc\u200c\u0634\u0648\u0646\u062f\u060c \u0627\u06af\u0631\u0686\u0647 \u0627\u06cc\u0646\u200c\u0647\u0627 \u0645\u0645\u06a9\u0646 \u0627\u0633\u062a \u0648\u06cc\u0698\u06af\u06cc \u0627\u062e\u062a\u0635\u0627\u0635\u06cc \u0628\u06cc\u0645\u0627\u0631\u06cc \u0632\u0645\u06cc\u0646\u0647\u200c\u0627\u06cc \u0646\u0628\u0627\u0634\u0646\u062f \u06a9\u0647 \u0628\u0647\u200c\u0639\u0644\u062a \u0622\u0646 \u0627\u0633\u067e\u0644\u0646\u06a9\u062a\u0648\u0645\u06cc \u0627\u0646\u062c\u0627\u0645 \u0634\u062f\u0647 \u0627\u0633\u062a.<\/span><\/p>\n

      \u062a\u0631\u0648\u0645\u0628\u0648\u0633\u06cc\u062a\u0648\u0632 (thrombocytosis) \u0648 \u0644\u06a9\u0648\u0633\u06cc\u062a\u0648\u0632 \u0646\u0648\u062a\u0631\u0648\u0641\u06cc\u0644\u06cc (neutrophil leucocytosis) \u067e\u0633 \u0627\u0632 \u0627\u0633\u067e\u0644\u0646\u06a9\u062a\u0648\u0645\u06cc \u0634\u0627\u06cc\u0639 \u0647\u0633\u062a\u0646\u062f\u060c \u0627\u06af\u0631\u0686\u0647 \u0628\u0627 \u06af\u0630\u0634\u062a \u0632\u0645\u0627\u0646 \u062a\u0639\u062f\u0627\u062f \u067e\u0644\u0627\u06a9\u062a\u200c\u0647\u0627 (platelets) \u06cc\u0627 \u0646\u0648\u062a\u0631\u0648\u0641\u06cc\u0644\u200c\u0647\u0627 \u0645\u0645\u06a9\u0646 \u0627\u0633\u062a \u0628\u0647 \u062d\u0627\u0644\u062a \u0637\u0628\u06cc\u0639\u06cc \u0628\u0631\u06af\u0631\u062f\u062f.<\/span><\/p>\n[\/vc_column_text][vc_separator color=”blue” border_width=”2″ css=””][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css=””]\n

      \u0633\u0624\u0627\u0644 35<\/span><\/h2>\n[\/vc_column_text][vc_column_text css=””]\n

      \u0634\u06a9\u0644 35 \u0644\u0627\u0645 \u062e\u0648\u0646 \u0627\u0632 \u06cc\u06a9 \u0645\u0631\u062f \u06f6\u06f8 \u0633\u0627\u0644\u0647 \u06a9\u0647 \u062f\u0686\u0627\u0631 \u06a9\u0645\u200c\u062e\u0648\u0646\u06cc (anaemic) \u0648 \u06a9\u0628\u0648\u062f\u06cc (bruised) \u0627\u0633\u062a. \u062a\u0634\u062e\u06cc\u0635 \u0686\u06cc\u0633\u062a\u061f<\/span><\/p>\n[\/vc_column_text][vc_single_image image=”112380″ img_size=”full” css=””][vc_column_text css=””]\n

      \u067e\u0627\u0633\u062e<\/span><\/strong><\/p>\n

        \n
      • \u062f\u0631 \u0627\u06cc\u0646 \u0644\u0627\u0645 \u062e\u0648\u0646\u060c \u062a\u0639\u062f\u0627\u062f \u0632\u06cc\u0627\u062f\u06cc \u0633\u0644\u0648\u0644 \u0628\u0644\u0627\u0633\u062a (blast cells) \u062f\u06cc\u062f\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f.<\/span><\/li>\n
      • \u0633\u0644\u0648\u0644\u200c\u0647\u0627 \u0628\u0647\u200c\u0637\u0648\u0631 \u0642\u0627\u0628\u0644\u200c\u062a\u0648\u062c\u0647\u06cc \u067e\u0644\u0626\u0648\u0645\u0648\u0631\u0641\u06cc\u06a9 (pleomorphic) \u0647\u0633\u062a\u0646\u062f\u061b \u0628\u0631\u062e\u06cc \u062f\u0627\u0631\u0627\u06cc \u0646\u0633\u0628\u062a \u0628\u0627\u0644\u0627\u06cc \u0647\u0633\u062a\u0647 \u0628\u0647 \u0633\u06cc\u062a\u0648\u067e\u0644\u0627\u0633\u0645 (high nuclear\u2011cytoplasmic ratios) \u0628\u0648\u062f\u0647 \u0648 \u062a\u0639\u062f\u0627\u062f\u06cc \u0627\u0632 \u0622\u0646\u200c\u0647\u0627 \u0641\u0631\u0645\u200c\u0647\u0627\u06cc \u062f\u0648\u200c\u0647\u0633\u062a\u0647\u200c\u0627\u06cc (binucleate forms) \u0646\u0634\u0627\u0646 \u0645\u06cc\u200c\u062f\u0647\u0646\u062f.<\/span><\/li>\n
      • \u0627\u06cc\u0646 \u06cc\u06a9 \u0644\u0648\u0633\u0645\u06cc \u062d\u0627\u062f (acute leukaemia) \u0627\u0633\u062a \u0648 \u0628\u0631\u0631\u0633\u06cc\u200c\u0647\u0627\u06cc \u0628\u06cc\u0634\u062a\u0631 \u062a\u0623\u06cc\u06cc\u062f \u06a9\u0631\u062f \u06a9\u0647 \u0627\u06cc\u0646 \u0644\u0648\u0633\u0645\u06cc \u0627\u0632 \u062f\u0648\u062f\u0645\u0627\u0646 \u0645\u06cc\u0644\u0648\u0626\u06cc\u062f\u06cc (myeloid lineage) \u0628\u0648\u062f\u0647 \u0648 \u0628\u0647\u200c\u0637\u0648\u0631 \u062e\u0627\u0635 \u0632\u06cc\u0631\u06af\u0631\u0648\u0647 FAB \u0646\u0648\u0639 M5 \u0627\u0633\u062a.<\/span><\/li>\n
      • \u0633\u0644\u0648\u0644\u200c\u0647\u0627\u06cc \u062f\u0648\u200c\u0647\u0633\u062a\u0647\u200c\u0627\u06cc (binucleate forms) \u0628\u0631\u0627\u06cc \u0644\u0648\u0633\u0645\u06cc \u0645\u0648\u0646\u0648\u0633\u06cc\u062a\u06cc\u06a9 \u062d\u0627\u062f (acute monocytic leukaemia) \u062a\u06cc\u067e\u06cc\u06a9 \u0647\u0633\u062a\u0646\u062f.<\/span><\/li>\n<\/ul>\n[\/vc_column_text][vc_separator color=”blue” border_width=”2″ css=””][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css=””]\n

        \u0633\u0624\u0627\u0644 36<\/span><\/h2>\n[\/vc_column_text][vc_column_text css=””]\n

        \u0627\u0644\u06a9\u062a\u0631\u0648\u0641\u0648\u0631\u0632 \u0647\u0645\u0648\u06af\u0644\u0648\u0628\u06cc\u0646 \u0631\u0648\u06cc \u0627\u0633\u062a\u0627\u062a \u0633\u0644\u0648\u0644\u06cc \u062f\u0631 pH \u0628\u0631\u0627\u0628\u0631 8.6\u061b \u0646\u0642\u0627\u0637 \u0633\u06cc\u0627\u0647 \u0645\u062d\u0644 \u0634\u0631\u0648\u0639 \u0645\u0647\u0627\u062c\u0631\u062a \u0631\u0627 \u0646\u0634\u0627\u0646 \u0645\u06cc\u200c\u062f\u0647\u0646\u062f. \u0645\u0648\u0642\u0639\u06cc\u062a \u0647\u0645\u0648\u06af\u0644\u0648\u0628\u06cc\u0646\u200c\u0647\u0627\u06cc A\u060c S \u0648 C \u062f\u0631 \u0632\u06cc\u0631 \u0645\u0634\u062e\u0635 \u0634\u062f\u0647 \u0627\u0633\u062a. \u0627\u06cc\u0646 \u062a\u0635\u0648\u06cc\u0631 \u0686\u0647 \u0686\u06cc\u0632\u06cc \u0631\u0627 \u0646\u0634\u0627\u0646 \u0645\u06cc\u200c\u062f\u0647\u062f\u061f<\/span><\/p>\n[\/vc_column_text][vc_single_image image=”112382″ img_size=”full” css=””][vc_column_text css=””]\n

        \u067e\u0627\u0633\u062e<\/strong><\/span><\/p>\n

        \u0628\u0627\u0646\u062f\u0647\u0627 \u062f\u0631 \u0645\u0648\u0642\u0639\u06cc\u062a \u0647\u0645\u0648\u06af\u0644\u0648\u0628\u06cc\u0646\u200c\u0647\u0627\u06cc A \u0648 S \u062f\u06cc\u062f\u0647 \u0645\u06cc\u200c\u0634\u0648\u0646\u062f.<\/span><\/p>\n

        \u0634\u062f\u062a \u0627\u06cc\u0646 \u0628\u0627\u0646\u062f\u0647\u0627 \u0628\u0631\u0627\u0628\u0631 (equal intensity) \u0627\u0633\u062a \u06a9\u0647 \u0646\u0634\u0627\u0646\u200c\u062f\u0647\u0646\u062f\u0647 \u00a0\u0635\u0641\u062a \u0633\u0644\u0648\u0644 \u062f\u0627\u0633\u06cc\u200c\u0634\u06a9\u0644 (sickle cell trait) \u0627\u0633\u062a.<\/span><\/p>\n

        \u0645\u0647\u0645 \u0627\u0633\u062a \u06a9\u0647 \u0628\u062f\u0627\u0646\u06cc\u0645 \u0628\u06cc\u0645\u0627\u0631 \u0628\u0647\u200c\u062a\u0627\u0632\u06af\u06cc \u062e\u0648\u0646 \u062f\u0631\u06cc\u0627\u0641\u062a \u0646\u06a9\u0631\u062f\u0647 \u0628\u0627\u0634\u062f (not been transfused recently)\u060c \u0632\u06cc\u0631\u0627 \u062f\u0631 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646\u06cc \u06a9\u0647 \u0647\u0645\u0648\u0632\u06cc\u06af\u0648\u062a HbS \u0647\u0633\u062a\u0646\u062f (homozygous for HbS)\u060c \u062a\u0632\u0631\u06cc\u0642 \u062e\u0648\u0646 \u0645\u06cc\u200c\u062a\u0648\u0627\u0646\u062f \u0638\u0627\u0647\u0631 \u0635\u0641\u062a \u062f\u0627\u0633\u06cc\u200c\u0634\u06a9\u0644 \u0631\u0627 \u062a\u0642\u0644\u06cc\u062f \u06a9\u0646\u062f.<\/span><\/p>\n

        \u0647\u0645\u0686\u0646\u06cc\u0646 \u0628\u0627\u06cc\u062f \u0628\u0647 \u06cc\u0627\u062f \u062f\u0627\u0634\u062a \u06a9\u0647 \u0628\u0631\u062e\u06cc \u0647\u0645\u0648\u06af\u0644\u0648\u0628\u06cc\u0646\u200c\u0647\u0627\u06cc \u062f\u06cc\u06af\u0631 (other haemoglobins) \u0646\u06cc\u0632 \u062a\u062d\u0631\u06a9 \u0645\u0634\u0627\u0628\u0647 HbS \u062f\u0627\u0631\u0646\u062f\u060c \u0645\u0627\u0646\u0646\u062f HbD.<\/span><\/p>\n

        \u0645\u06cc\u200c\u062a\u0648\u0627\u0646 \u0627\u06cc\u0646 \u0645\u0648\u0627\u0631\u062f \u0631\u0627 \u0628\u0647\u200c\u0633\u0627\u062f\u06af\u06cc \u0628\u0627 \u0627\u0646\u062c\u0627\u0645 \u062a\u0633\u062a \u062d\u0644\u0627\u0644\u06cc\u062a \u062f\u0627\u0633\u06cc\u200c\u0634\u06a9\u0644 (sickle solubility test \/ sickledex)<\/span><\/p>\n

        \u06cc\u0627 \u0628\u0627 \u0627\u0646\u062c\u0627\u0645 \u0627\u0644\u06a9\u062a\u0631\u0648\u0641\u0648\u0631\u0632 \u062f\u0631 pH \u06cc\u0627 \u0645\u062d\u06cc\u0637\u200c\u0647\u0627\u06cc \u0645\u062a\u0641\u0627\u0648\u062a (electrophoresis under altered pH and media) \u062a\u0645\u0627\u06cc\u0632 \u062f\u0627\u062f.<\/span><\/p>\n[\/vc_column_text][vc_separator color=”blue” border_width=”2″ css=””][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css=””]\n

        \u0633\u0624\u0627\u0644 37<\/span><\/h2>\n[\/vc_column_text][vc_column_text css=””]\n

        \u0627\u06cc\u0646 \u062a\u0635\u0648\u06cc\u0631 \u0645\u0631\u0628\u0648\u0637 \u0628\u0647 \u062f\u0633\u062a \u06cc\u06a9 \u0628\u06cc\u0645\u0627\u0631 \u06f3\u06f0 \u0631\u0648\u0632 \u067e\u0633 \u0627\u0632 \u067e\u06cc\u0648\u0646\u062f \u0645\u063a\u0632 \u0627\u0633\u062a\u062e\u0648\u0627\u0646 \u0622\u0644\u0648\u0698\u0646\u06cc\u06a9 \u0645\u06cc\u200c\u0628\u0627\u0634\u062f. \u0627\u06cc\u0646 \u062a\u0635\u0648\u06cc\u0631 \u0686\u0647 \u0686\u06cc\u0632\u06cc \u0631\u0627 \u0646\u0634\u0627\u0646 \u0645\u06cc\u200c\u062f\u0647\u062f \u0648 \u062a\u0634\u062e\u06cc\u0635 \u0686\u06cc\u0633\u062a\u061f<\/span><\/p>\n[\/vc_column_text][vc_single_image image=”112384″ img_size=”full” css=””][vc_column_text css=””]\n

        \u067e\u0627\u0633\u062e<\/span><\/strong><\/p>\n

        \u0627\u06cc\u0646 \u062a\u0635\u0648\u06cc\u0631\u060c \u0648\u06cc\u0698\u06af\u06cc\u200c\u0647\u0627\u06cc \u06a9\u0644\u0627\u0633\u06cc\u06a9 \u0628\u06cc\u0645\u0627\u0631\u06cc \u067e\u06cc\u0648\u0646\u062f \u0639\u0644\u06cc\u0647 \u0645\u06cc\u0632\u0628\u0627\u0646 \u062d\u0627\u062f \u0631\u0627 \u0646\u0634\u0627\u0646 \u0645\u06cc\u200c\u062f\u0647\u062f \u06a9\u0647 \u0628\u0627 \u0627\u0631\u06cc\u062a\u0645\u0627\u06cc \u0648\u0627\u0636\u062d (marked erythema) \u0648 \u0631\u0627\u0634 \u0645\u0627\u06a9\u0648\u0644\u0627\u0631 (macular rash) \u0645\u0634\u062e\u0635 \u0645\u06cc\u200c\u0634\u0648\u062f \u0648 \u0645\u0639\u0645\u0648\u0644\u0627\u064b \u0627\u0628\u062a\u062f\u0627 \u062f\u0631 \u06a9\u0641 \u062f\u0633\u062a\u200c (palms) \u0648 \u06a9\u0641 \u067e\u0627\u0647\u0627 (soles) \u062f\u06cc\u062f\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f. GVHD \u062d\u0627\u062f \u062f\u0631 \u0627\u062b\u0631 \u067e\u06cc\u0648\u0646\u062f \u0644\u0646\u0641\u0648\u0633\u06cc\u062a \u0647\u0627\u06cc \u0627\u06cc\u0645\u0646\u06cc \u0633\u0627\u0632 \u0627\u0647\u062f\u0627 \u06a9\u0646\u0646\u062f\u0647 \u0631\u062e \u0645\u06cc \u062f\u0647\u062f.\u06a9\u0647 \u0622\u0646\u062a\u06cc\u200c\u0698\u0646\u200c\u0647\u0627\u06cc HLA \u0631\u0648\u06cc \u067e\u0648\u0633\u062a \u06af\u06cc\u0631\u0646\u062f\u0647\u0631\u0627 \u0634\u0646\u0627\u0633\u0627\u06cc\u06cc \u0645\u06cc\u200c\u06a9\u0646\u0646\u062f. \u0627\u06cc\u0646 \u0644\u0646\u0641\u0648\u0633\u06cc\u062a\u200c\u0647\u0627 \u0645\u0648\u062c\u0628 \u0627\u06cc\u062c\u0627\u062f \u0631\u0627\u0634 \u0627\u0631\u06cc\u062a\u0645\u0627\u062a\u0648\u06cc \u0642\u0627\u0628\u0644\u200c\u062a\u0648\u062c\u0647\u06cc (intense erythematous rash) \u0645\u06cc\u200c\u0634\u0648\u0646\u062f \u06a9\u0647 \u0645\u0645\u06a9\u0646 \u0627\u0633\u062a \u0628\u0647 \u0647\u0645 \u067e\u06cc\u0648\u0633\u062a\u0647 (confluent) \u06af\u0631\u062f\u062f. \u062f\u0631 \u0645\u0631\u0627\u062d\u0644 \u0627\u0648\u0644\u06cc\u0647\u060c \u0627\u06cc\u0646 \u062d\u0627\u0644\u062a \u0645\u0645\u06a9\u0646 \u0627\u0633\u062a \u0627\u0632 \u0646\u0638\u0631 \u0638\u0627\u0647\u0631\u06cc \u0634\u0628\u06cc\u0647 \u0631\u0627\u0634 \u062f\u0627\u0631\u0648\u06cc\u06cc (drug\u2011induced rash) \u0628\u0627\u0634\u062f\u060c \u0627\u0645\u0627 \u062f\u0631\u06af\u06cc\u0631\u06cc \u0645\u0634\u062e\u0635 \u06a9\u0641 \u062f\u0633\u062a \u0648 \u067e\u0627\u0647\u0627 (predilection to affect palms and soles) \u0642\u0648\u06cc\u0627\u064b \u0628\u0647 \u0646\u0641\u0639 GVHD \u0627\u0633\u062a. \u062f\u0631 \u0686\u0646\u06cc\u0646 \u0645\u0648\u0627\u0631\u062f\u06cc\u060c \u0628\u06cc\u0648\u067e\u0633\u06cc \u067e\u0648\u0633\u062a (skin biopsy) \u0645\u06cc\u200c\u062a\u0648\u0627\u0646\u062f \u062f\u0631 \u062a\u0623\u06cc\u06cc\u062f \u062a\u0634\u062e\u06cc\u0635 \u0645\u0641\u06cc\u062f \u0628\u0627\u0634\u062f. \u0644\u0646\u0641\u0648\u0633\u06cc\u062a\u200c\u0647\u0627\u06cc \u0627\u0647\u062f\u0627\u06a9\u0646\u0646\u062f\u0647 \u00a0\u0627\u06cc\u0645\u0646\u06cc\u200c\u0633\u0627\u0632 (immunocompetent donor lymphocytes) \u0647\u0645\u0686\u0646\u06cc\u0646 \u0642\u0627\u062f\u0631\u0646\u062f \u0622\u0646\u062a\u06cc\u200c\u0698\u0646\u200c\u0647\u0627\u06cc HLA \u062f\u0631 \u06a9\u0628\u062f (liver) \u0648 \u0631\u0648\u062f\u0647 (gut) \u0631\u0627 \u0646\u06cc\u0632 \u0634\u0646\u0627\u0633\u0627\u06cc\u06cc \u06a9\u0631\u062f\u0647 \u0648 \u0627\u06cc\u0646 \u0627\u0646\u062f\u0627\u0645\u200c\u0647\u0627 \u0631\u0627 \u062f\u0631\u06af\u06cc\u0631 \u06a9\u0646\u0646\u062f. \u062a\u062e\u0631\u06cc\u0628 \u0647\u067e\u0627\u062a\u0648\u0633\u06cc\u062a\u200c\u0647\u0627 (hepatocyte destruction) \u0645\u0645\u06a9\u0646 \u0627\u0633\u062a \u0645\u0646\u062c\u0631 \u0628\u0647 \u0647\u06cc\u067e\u0631\u0628\u06cc\u0644\u06cc\u200c\u0631\u0648\u0628\u06cc\u0646\u0645\u06cc (hyperbilirubinaemia) \u0648 \u0633\u0627\u06cc\u0631 \u0639\u0644\u0627\u0626\u0645 \u0627\u062e\u062a\u0644\u0627\u0644 \u0639\u0645\u0644\u06a9\u0631\u062f \u06a9\u0628\u062f\u06cc (impaired hepatic function) \u0634\u0648\u062f. \u062f\u0631 \u0645\u0648\u0627\u0631\u062f\u06cc \u06a9\u0647 GVHD \u0631\u0648\u062f\u0647 \u0631\u0627 \u062f\u0631\u06af\u06cc\u0631 \u0645\u06cc\u200c\u06a9\u0646\u062f\u060c \u0628\u06cc\u0645\u0627\u0631 \u0645\u0639\u0645\u0648\u0644\u0627\u064b \u062f\u0686\u0627\u0631 \u0627\u0633\u0647\u0627\u0644 \u062d\u062c\u06cc\u0645 \u0648 \u0622\u0628\u06a9\u06cc (diarrhoea of large volume and watery consistency) \u0645\u06cc\u200c\u0634\u0648\u062f. \u062a\u0634\u062e\u06cc\u0635 \u0628\u06cc\u0645\u0627\u0631\u06cc \u067e\u06cc\u0648\u0646\u062f \u0639\u0644\u06cc\u0647 \u0645\u06cc\u0632\u0628\u0627\u0646 \u062d\u0627\u062f (Acute GVHD \u067e\u0633 \u0627\u0632 \u067e\u06cc\u0648\u0646\u062f \u0645\u063a\u0632 \u0627\u0633\u062a\u062e\u0648\u0627\u0646 \u0622\u0644\u0648\u0698\u0646\u06cc\u06a9 \u0627\u0633\u062a.<\/span><\/p>\n[\/vc_column_text][vc_separator color=”blue” border_width=”2″ css=””][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css=””]\n

        \u0633\u0624\u0627\u0644 38<\/span><\/h2>\n[\/vc_column_text][vc_column_text css=””]\n

        \u0634\u06a9\u0644 38 \u06af\u0633\u062a\u0631\u0634 \u062e\u0648\u0646 \u0645\u062d\u06cc\u0637\u06cc \u0627\u0632 \u06cc\u06a9 \u0628\u0627\u0646\u0648\u06cc \u06f5\u06f8 \u0633\u0627\u0644\u0647 \u0627\u0633\u062a \u06a9\u0647 \u062f\u0686\u0627\u0631 \u06a9\u0645\u200c\u062e\u0648\u0646\u06cc (anaemic)\u060c \u062a\u0631\u0648\u0645\u0628\u0648\u0633\u06cc\u062a\u0648\u067e\u0646\u06cc (thrombocytopenic) \u0648 \u0644\u06a9\u0648\u067e\u0646\u06cc (leucopenic) \u0645\u06cc\u200c\u0628\u0627\u0634\u062f.<\/span><\/p>\n

        \u062f\u0631 \u0645\u0639\u0627\u06cc\u0646\u0647\u060c \u0627\u0633\u067e\u0644\u0646\u0648\u0645\u06af\u0627\u0644\u06cc (splenomegaly) \u0645\u0634\u0627\u0647\u062f\u0647 \u0634\u062f \u0627\u0645\u0627 \u0644\u0646\u0641\u0627\u062f\u0646\u0648\u067e\u0627\u062a\u06cc (lymphadenopathy) \u0648\u062c\u0648\u062f \u0646\u062f\u0627\u0634\u062a.<\/span><\/p>\n

        \u062f\u0631 \u0622\u0633\u067e\u06cc\u0631\u0627\u0633\u06cc\u0648\u0646 \u0645\u063a\u0632 \u0627\u0633\u062a\u062e\u0648\u0627\u0646 \u0686\u06cc\u0632\u06cc \u0628\u062f\u0633\u062a \u0646\u06cc\u0627\u0645\u062f.\u06af\u0633\u062a\u0631\u0634 \u062e\u0648\u0646 \u0645\u062d\u06cc\u0637\u06cc \u0686\u0647 \u0686\u06cc\u0632\u06cc \u0631\u0627 \u0646\u0634\u0627\u0646 \u0645\u06cc\u200c\u062f\u0647\u062f \u0648 \u0645\u062d\u062a\u0645\u0644\u200c\u062a\u0631\u06cc\u0646 \u062a\u0634\u062e\u06cc\u0635 \u0686\u06cc\u0633\u062a\u061f<\/span><\/p>\n[\/vc_column_text][vc_single_image image=”112387″ img_size=”full” css=””][vc_column_text css=””]\n

        \u067e\u0627\u0633\u062e<\/span><\/strong><\/p>\n

        \u06af\u0633\u062a\u0631\u0634 \u062e\u0648\u0646 \u0645\u062d\u06cc\u0637\u06cc \u0648\u062c\u0648\u062f \u0644\u0646\u0641\u0648\u0633\u06cc\u062a\u200c\u0647\u0627\u06cc \u0622\u062a\u06cc\u067e\u06cc\u06a9 (atypical lymphocytes) \u0631\u0627 \u0646\u0634\u0627\u0646 \u0645\u06cc\u200c\u062f\u0647\u062f \u06a9\u0647 \u0645\u06cc\u0632\u0627\u0646 \u0645\u062a\u0641\u0627\u0648\u062a\u06cc \u0627\u0632 \u0633\u06cc\u062a\u0648\u067e\u0644\u0627\u0633\u0645 \u062f\u0627\u0631\u0646\u062f.<\/span><\/p>\n

        \u062f\u0631 \u0628\u0631\u062e\u06cc \u0627\u0632 \u0627\u06cc\u0646 \u0633\u0644\u0648\u0644\u200c\u0647\u0627\u060c \u0633\u06cc\u062a\u0648\u067e\u0644\u0627\u0633\u0645 \u0646\u0627\u0645\u0646\u0638\u0645 \u0648 \u067e\u0631\u0632\u062f\u0627\u0631 \u0628\u0627 \u062d\u0627\u0634\u06cc\u0647 \u0646\u0627\u0635\u0627\u0641 (cytoplasm with marked border irregularity) \u062f\u06cc\u062f\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f\u060c \u06a9\u0647 \u0628\u0647 \u0647\u0645\u06cc\u0646 \u062f\u0644\u06cc\u0644 \u0627\u06cc\u0646 \u0628\u06cc\u0645\u0627\u0631\u06cc \u0628\u0647\u200c\u0637\u0648\u0631 \u0645\u0639\u0645\u0648\u0644 \u00ab\u0644\u0648\u0633\u0645\u06cc \u0633\u0644\u0648\u0644 \u0645\u0648\u06cc\u06cc\u00bb (hairy cell leukaemia) \u0646\u0627\u0645\u06cc\u062f\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f.<\/span><\/p>\n

        \u062f\u0631 \u0627\u06cc\u0646 \u0628\u06cc\u0645\u0627\u0631\u06cc \u0641\u06cc\u0628\u0631\u0648\u0632 \u0645\u063a\u0632 \u0627\u0633\u062a\u062e\u0648\u0627\u0646 (marrow fibrosis) \u0634\u0627\u06cc\u0639 \u0627\u0633\u062a \u0648 \u0647\u0645\u06cc\u0646 \u0645\u0648\u0636\u0648\u0639 \u0628\u0627\u0639\u062b \u0633\u062e\u062a\u06cc \u062f\u0631 \u0627\u0646\u062c\u0627\u0645 \u0622\u0633\u067e\u06cc\u0631\u0627\u0633\u06cc\u0648\u0646 \u0645\u063a\u0632 \u0627\u0633\u062a\u062e\u0648\u0627\u0646 (difficulty in marrow aspiration) \u0645\u06cc\u200c\u0634\u0648\u062f \u2014 \u0627\u0635\u0637\u0644\u0627\u062d\u0627\u064b \u0628\u0647 \u0622\u0646 \u201cdry tap\u201d \u06af\u0641\u062a\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f.<\/span><\/p>\n

        \u062a\u0634\u062e\u06cc\u0635 \u0631\u0627 \u0645\u06cc\u200c\u062a\u0648\u0627\u0646 \u0628\u0647 \u0631\u0648\u0634\u200c\u0647\u0627\u06cc \u0632\u06cc\u0631 \u062a\u0623\u06cc\u06cc\u062f \u06a9\u0631\u062f:<\/span><\/p>\n

          \n
        • \u0633\u0627\u06cc\u062a\u0648\u0634\u06cc\u0645\u06cc (cytochemistry) \u06cc\u0627<\/span><\/li>\n
        • \u0627\u06cc\u0645\u0648\u0646\u0648\u0641\u0646\u0648\u062a\u0627\u06cc\u067e\u06cc\u0646\u06af (immunophenotyping).<\/span><\/li>\n<\/ul>\n

          \u062f\u0631\u0645\u0627\u0646 \u0645\u0639\u0645\u0648\u0644\u0627\u064b \u0627\u0633\u067e\u0644\u0646\u06a9\u062a\u0648\u0645\u06cc (splenectomy) \u0627\u0633\u062a\u060c \u0628\u0647\u200c\u0648\u06cc\u0698\u0647 \u0632\u0645\u0627\u0646\u06cc \u06a9\u0647 \u0628\u0632\u0631\u06af\u06cc \u0637\u062d\u0627\u0644 (spleen) \u0642\u0627\u0628\u0644\u200c\u062a\u0648\u062c\u0647 \u0628\u0627\u0634\u062f.<\/span><\/p>\n

          \u062f\u0631 \u0645\u0648\u0627\u0631\u062f\u06cc \u06a9\u0647 \u0627\u0633\u067e\u0644\u0646\u0648\u0645\u06af\u0627\u0644\u06cc \u0648\u062c\u0648\u062f \u0646\u062f\u0627\u0631\u062f \u06cc\u0627 \u0628\u0631\u062f\u0627\u0634\u062a\u0646 \u0637\u062d\u0627\u0644 \u0645\u0624\u062b\u0631 \u0646\u0628\u0648\u062f\u0647 \u0627\u0633\u062a\u060c<\/span><\/p>\n

          \u0645\u06cc\u200c\u062a\u0648\u0627\u0646 \u0627\u0632 \u0634\u06cc\u0645\u06cc\u200c\u062f\u0631\u0645\u0627\u0646\u06cc (chemotherapy) \u0628\u0627 \u062f\u0627\u0631\u0648\u0647\u0627\u06cc\u06cc \u0645\u0627\u0646\u0646\u062f<\/span><\/p>\n

          \u062f\u0626\u0648\u06a9\u0633\u06cc\u200c\u0641\u0648\u0631\u0648\u0645\u0627\u06cc\u0633\u06cc\u0646 (deoxycoformycin) \u06cc\u0627 \u0627\u06cc\u0646\u062a\u0631\u0641\u0631\u0648\u0646 (interferon) \u0646\u06cc\u0632 \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u06a9\u0631\u062f.<\/span><\/p>\n[\/vc_column_text][vc_column_text css=””]\n

          \u062a\u0634\u062e\u06cc\u0635 \u0644\u0648\u0633\u0645\u06cc \u0633\u0644\u0648\u0644 \u0645\u0648\u06cc\u06cc (Hairy Cell Leukaemia) \u0627\u0633\u062a \u0628\u0627 \u0648\u06cc\u0698\u06af\u06cc\u200c\u0647\u0627\u06cc \u06a9\u0644\u0627\u0633\u06cc\u06a9:<\/span><\/p>\n

            \n
          • \u067e\u0627\u0646\u200c\u0633\u06cc\u062a\u0648\u067e\u0646\u06cc (pancytopenia: \u06a9\u0645\u200c\u062e\u0648\u0646\u06cc\u060c \u0644\u06a9\u0648\u067e\u0646\u06cc\u060c \u062a\u0631\u0648\u0645\u0628\u0648\u0633\u06cc\u062a\u0648\u067e\u0646\u06cc)\u060c<\/span><\/li>\n
          • \u0627\u0633\u067e\u0644\u0646\u0648\u0645\u06af\u0627\u0644\u06cc\u060c<\/span><\/li>\n
          • dry tap\u060c<\/span><\/li>\n
          • \u0648 \u062d\u0636\u0648\u0631 \u0633\u0644\u0648\u0644\u200c\u0647\u0627\u06cc \u0645\u0648\u06cc\u06cc \u062f\u0631 \u062e\u0648\u0646 \u0645\u062d\u06cc\u0637\u06cc.<\/span><\/li>\n<\/ul>\n[\/vc_column_text][vc_separator color=”blue” border_width=”2″ css=””][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css=””]\n

            \u0633\u0624\u0627\u0644 39<\/span><\/h2>\n[\/vc_column_text][vc_column_text css=””]\n

            \u0634\u06a9\u0644 39 \u06af\u0633\u062a\u0631\u0634 \u062e\u0648\u0646 \u0645\u062d\u06cc\u0637\u06cc \u0645\u0631\u0628\u0648\u0637 \u0628\u0647 \u06cc\u06a9 \u0628\u0627\u0646\u0648\u06cc \u06f4\u06f6 \u0633\u0627\u0644\u0647 \u0627\u0633\u062a \u06a9\u0647 \u0627\u0632 \u062e\u0648\u0646\u0631\u06cc\u0632\u06cc \u0644\u062b\u0647\u200c\u0647\u0627 (bleeding gums) \u0634\u06a9\u0627\u06cc\u062a \u062f\u0627\u0634\u062a\u0647 \u0648 \u062a\u0648\u0633\u0637 \u062f\u0646\u062f\u0627\u0646\u200c\u067e\u0632\u0634\u06a9 \u0645\u0639\u0627\u06cc\u0646\u0647 \u0634\u062f\u0647 \u0627\u0633\u062a.\u062f\u0646\u062f\u0627\u0646\u200c\u067e\u0632\u0634\u06a9 \u0647\u06cc\u067e\u0631\u062a\u0631\u0648\u0641\u06cc \u0644\u062b\u0647 (gum hypertrophy) \u0631\u0627 \u0645\u0634\u0627\u0647\u062f\u0647 \u06a9\u0631\u062f\u0647 \u0648 \u0627\u0648 \u0631\u0627 \u0628\u0631\u0627\u06cc \u0627\u0646\u062c\u0627\u0645 \u0634\u0645\u0627\u0631\u0634 \u06a9\u0627\u0645\u0644 \u0633\u0644\u0648\u0644\u200c\u0647\u0627\u06cc \u062e\u0648\u0646\u06cc \u0627\u0631\u062c\u0627\u0639 \u062f\u0627\u062f\u0647 \u0627\u0633\u062a.\u062a\u0634\u062e\u06cc\u0635 \u0686\u06cc\u0633\u062a\u061f<\/span><\/p>\n[\/vc_column_text][vc_single_image image=”112389″ img_size=”full” css=””][vc_column_text css=””]\n

            \u00a0\u067e\u0627\u0633\u062e<\/strong><\/span><\/p>\n

            \u062f\u0631 \u06af\u0633\u062a\u0631\u0634 \u062e\u0648\u0646 \u0645\u062d\u06cc\u0637\u06cc \u060c \u062a\u0639\u062f\u0627\u062f\u06cc \u0633\u0644\u0648\u0644 \u0628\u0632\u0631\u06af \u0648 \u063a\u06cc\u0631\u0637\u0628\u06cc\u0639\u06cc (large, bizarre cells) \u0628\u0627 \u0633\u06cc\u062a\u0648\u067e\u0644\u0627\u0633\u0645 \u0641\u0631\u0627\u0648\u0627\u0646 (abundant cytoplasm) \u062f\u06cc\u062f\u0647 \u0645\u06cc\u200c\u0634\u0648\u0646\u062f. \u062f\u0631 \u0686\u0646\u062f \u0645\u0648\u0631\u062f \u0627\u0632 \u0627\u06cc\u0646 \u0633\u0644\u0648\u0644\u200c\u0647\u0627\u060c \u0648\u0627\u06a9\u0648\u0626\u0644\u200c\u0647\u0627\u06cc \u0628\u0631\u062c\u0633\u062a\u0647 (prominent vacuolation) \u0645\u0634\u0627\u0647\u062f\u0647 \u0645\u06cc\u200c\u06af\u0631\u062f\u062f.<\/span><\/p>\n

            \u0647\u0633\u062a\u0647 \u0633\u0644\u0648\u0644\u200c\u0647\u0627 \u062f\u0627\u0631\u0627\u06cc \u06a9\u0631\u0648\u0645\u0627\u062a\u06cc\u0646 \u0628\u0627\u0632 (open chromatin) \u0628\u0648\u062f\u0647 \u0648 \u06af\u0627\u0647\u06cc \u0686\u0646\u062f\u200c\u0647\u0633\u062a\u0647\u200c\u0627\u06cc (multiple nuclei) \u0647\u0633\u062a\u0646\u062f.<\/span><\/p>\n

            \u0627\u06cc\u0646 \u0646\u0645\u0627\u06cc \u0645\u06cc\u06a9\u0631\u0648\u0633\u06a9\u0648\u067e\u06cc \u0628\u06cc\u0627\u0646\u06af\u0631 \u0644\u0648\u0633\u0645\u06cc \u062d\u0627\u062f (acute leukaemia) \u0627\u0633\u062a. \u0648\u062c\u0648\u062f \u0633\u06cc\u062a\u0648\u067e\u0644\u0627\u0633\u0645 \u0632\u06cc\u0627\u062f \u0628\u0647 \u0647\u0645\u0631\u0627\u0647 \u0648\u0627\u06a9\u0648\u0626\u0644\u200c\u0647\u0627 \u0646\u0634\u0627\u0646\u200c\u062f\u0647\u0646\u062f\u0647 \u00a0\u062f\u0648\u062f\u0645\u0627\u0646 \u0645\u0648\u0646\u0648\u0633\u06cc\u062a\u06cc\u06a9 (monocytic lineage) \u0627\u0633\u062a \u06a9\u0647 \u0627\u06cc\u0646 \u062a\u0634\u062e\u06cc\u0635 \u0628\u0627 \u0628\u0631\u0631\u0633\u06cc\u200c\u0647\u0627\u06cc \u062a\u06a9\u0645\u06cc\u0644\u06cc (further investigation) \u0646\u06cc\u0632 \u062a\u0623\u06cc\u06cc\u062f \u0634\u062f. \u062f\u0631\u06af\u06cc\u0631\u06cc \u0628\u0627\u0641\u062a \u0644\u062b\u0647 (gum infiltration) \u06cc\u06a9 \u06cc\u0627\u0641\u062a\u0647\u0654 \u0634\u0627\u06cc\u0639 \u062f\u0631 \u0644\u0648\u0633\u0645\u06cc \u0645\u0648\u0646\u0648\u0633\u06cc\u062a\u06cc\u06a9 \u062d\u0627\u062f (acute monocytic leukaemia \u2013 AML M5) \u0627\u0633\u062a\u060c \u0627\u0645\u0627 \u0627\u06cc\u0646 \u062d\u0627\u0644\u062a \u0645\u06cc\u200c\u062a\u0648\u0627\u0646\u062f \u062f\u0631 \u0633\u0627\u06cc\u0631 \u0628\u0627\u0641\u062a\u200c\u0647\u0627 \u0627\u0632 \u062c\u0645\u0644\u0647 \u0635\u0641\u0627\u0642 (peritoneum)\u060c \u067e\u0631\u06cc\u06a9\u0627\u0631\u062f (pericardium) \u0648 \u067e\u0644\u0648\u0631 (pleura) \u0646\u06cc\u0632 \u0645\u0634\u0627\u0647\u062f\u0647 \u06af\u0631\u062f\u062f. \u062a\u0634\u062e\u06cc\u0635 \u0644\u0648\u0633\u0645\u06cc \u0645\u0648\u0646\u0648\u0633\u06cc\u062a\u06cc\u06a9 \u062d\u0627\u062f (Acute Monocytic Leukaemia \u2013 AML M5) \u0627\u0633\u062a.<\/span><\/p>\n

            \u0646\u06a9\u062a\u0647 \u0628\u0627\u0644\u06cc\u0646\u06cc:<\/span><\/strong><\/p>\n

            \u062f\u0631\u06af\u06cc\u0631\u06cc \u0644\u062b\u0647 \u0646\u0627\u0634\u06cc \u0627\u0632 \u0627\u0631\u062a\u0634\u0627\u062d \u0645\u0648\u0646\u0648\u0633\u06cc\u062a\u200c\u0647\u0627 \u06cc\u06a9\u06cc \u0627\u0632 \u0645\u0634\u062e\u0635\u0647\u200c\u0647\u0627\u06cc \u067e\u0627\u062a\u0648\u0644\u0648\u0698\u06cc\u06a9 \u0645\u0647\u0645 \u062f\u0631 AML \u0628\u0627 \u062f\u0648\u062f\u0645\u0627\u0646 \u0645\u0648\u0646\u0648\u0633\u06cc\u062a\u06cc\u06a9 \u0627\u0633\u062a.<\/span><\/p>\n[\/vc_column_text][vc_separator color=”blue” border_width=”2″ css=””][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css=””]\n

            \u0633\u0624\u0627\u0644 40<\/span><\/h2>\n[\/vc_column_text][vc_column_text css=””]\n

            \u0634\u06a9\u0644 40 \u0622\u0645\u0627\u062f\u0647\u200c\u0633\u0627\u0632\u06cc \u06a9\u0631\u0648\u0645\u0648\u0632\u0648\u0645\u06cc (chromosome preparation) \u0627\u0632 \u06cc\u06a9 \u0645\u0631\u062f \u06f4\u06f2 \u0633\u0627\u0644\u0647 \u0628\u0627 \u0627\u0633\u067e\u0644\u0646\u0648\u0645\u06af\u0627\u0644\u06cc (splenomegaly) \u0627\u0633\u062a. \u0686\u0647 \u0686\u06cc\u0632\u06cc \u062f\u0631 \u062a\u0635\u0648\u06cc\u0631 \u0646\u0634\u0627\u0646 \u062f\u0627\u062f\u0647 \u0634\u062f\u0647 \u0627\u0633\u062a\u061f<\/span><\/p>\n[\/vc_column_text][vc_single_image image=”112413″ img_size=”full” css=””][vc_column_text css=””]\n

            \u00a0\u067e\u0627\u0633\u062e\u00a0<\/span><\/strong><\/p>\n

            \u06a9\u0631\u0648\u0645\u0648\u0632\u0648\u0645\u06cc \u06a9\u0647 \u0628\u0627 \u0641\u0644\u0634 A \u0645\u0634\u062e\u0635 \u0634\u062f\u0647 \u0627\u0633\u062a\u060c \u06cc\u06a9 \u06a9\u0631\u0648\u0645\u0648\u0632\u0648\u0645 \u06f2\u06f2 \u063a\u06cc\u0631\u0637\u0628\u06cc\u0639\u06cc \u0645\u06cc\u200c\u0628\u0627\u0634\u062f. \u0627\u06cc\u0646 \u062a\u063a\u06cc\u06cc\u0631 \u062f\u0631 \u0627\u062b\u0631 \u062a\u0628\u0627\u062f\u0644 \u0628\u062e\u0634\u06cc \u0627\u0632 \u0628\u0627\u0632\u0648\u06cc \u0628\u0644\u0646\u062f \u06a9\u0631\u0648\u0645\u0648\u0632\u0648\u0645 \u06f9 \u0628\u0627 \u0628\u0627\u0632\u0648\u06cc \u0628\u0644\u0646\u062f \u06a9\u0631\u0648\u0645\u0648\u0632\u0648\u0645 \u06f2\u06f2 (exchange between the long arms of chromosomes 9 and 22) \u0627\u06cc\u062c\u0627\u062f \u0634\u062f\u0647 \u0627\u0633\u062a. \u062f\u0631 \u0646\u062a\u06cc\u062c\u0647\u060c \u06cc\u06a9 \u06a9\u0631\u0648\u0645\u0648\u0632\u0648\u0645 \u06f2\u06f2 \u06a9\u0648\u0686\u06a9\u200c\u062a\u0631 \u0627\u0632 \u062d\u0627\u0644\u062a \u0637\u0628\u06cc\u0639\u06cc (Philadelphia chromosome) \u0648 \u06cc\u06a9 \u06a9\u0631\u0648\u0645\u0648\u0632\u0648\u0645 \u06f9 \u0628\u0632\u0631\u06af\u200c\u062a\u0631 \u0627\u0632 \u062d\u0627\u0644\u062a \u0637\u0628\u06cc\u0639\u06cc (B) \u062a\u0634\u06a9\u06cc\u0644 \u0645\u06cc\u200c\u0634\u0648\u062f. \u0642\u0633\u0645\u062a\u06cc \u0627\u0632 \u0645\u0627\u062f\u0647 \u00a0\u0698\u0646\u062a\u06cc\u06a9\u06cc \u06a9\u0631\u0648\u0645\u0648\u0632\u0648\u0645 \u06f9 \u0634\u0627\u0645\u0644 \u0698\u0646 abl \u0627\u0633\u062a \u06a9\u0647 \u0628\u0647 \u0646\u0627\u062d\u06cc\u0647\u200c\u0627\u06cc \u0627\u0632 \u06a9\u0631\u0648\u0645\u0648\u0632\u0648\u0645 \u06f2\u06f2 \u0645\u0648\u0633\u0648\u0645 \u0628\u0647 breakpoint cluster region (bcr) \u0645\u0646\u062a\u0642\u0644 \u0645\u06cc\u200c\u06af\u0631\u062f\u062f. \u0645\u062d\u0635\u0648\u0644 \u0641\u06cc\u0648\u0698\u0646 \u062d\u0627\u0635\u0644 bcr\u2013abl \u06cc\u06a9 \u067e\u0631\u0648\u062a\u0626\u06cc\u0646 \u0628\u0632\u0631\u06af\u200c\u062a\u0631 \u0627\u0632 \u0645\u0639\u0645\u0648\u0644 \u062a\u0648\u0644\u06cc\u062f \u0645\u06cc\u200c\u06a9\u0646\u062f \u06a9\u0647 \u062f\u0627\u0631\u0627\u06cc \u062e\u0627\u0635\u06cc\u062a \u0622\u0646\u0632\u06cc\u0645 \u062a\u06cc\u0631\u0648\u0632\u06cc\u0646 \u06a9\u06cc\u0646\u0627\u0632 (tyrosine kinase enzyme) \u0627\u0633\u062a. \u0627\u06cc\u0646 \u06a9\u0631\u0648\u0645\u0648\u0632\u0648\u0645 \u0641\u06cc\u0644\u0627\u062f\u0644\u0641\u06cc\u0627 (Philadelphia chromosome) \u062f\u0631 \u0645\u0648\u0627\u0631\u062f \u0644\u0648\u0633\u0645\u06cc \u06af\u0631\u0627\u0646\u0648\u0644\u0648\u0633\u06cc\u062a\u06cc \u0645\u0632\u0645\u0646 (chronic granulocytic leukaemia \u2013 CML) \u0645\u0634\u0627\u0647\u062f\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f\u060c \u0648 \u062f\u0631 \u062d\u062f\u0648\u062f \u06f1\u06f0\u066a \u0627\u0632 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0645\u0628\u062a\u0644\u0627 \u0628\u0647 \u0644\u0648\u0633\u0645\u06cc \u0644\u0646\u0641\u0648\u0628\u0644\u0627\u0633\u062a\u06cc\u06a9 \u062d\u0627\u062f (acute lymphoblastic leukaemia \u2013 ALL) \u0646\u06cc\u0632 \u0648\u062c\u0648\u062f \u062f\u0627\u0631\u062f.<\/span><\/p>\n

            \u062f\u0631 \u0647\u0631\u06a9\u062f\u0627\u0645 \u0627\u0632 \u0627\u06cc\u0646 \u0634\u0631\u0627\u06cc\u0637\u060c \u0645\u062d\u0635\u0648\u0644 \u0641\u06cc\u0648\u0698\u0646 bcr\u2013abl \u062f\u0627\u0631\u0627\u06cc \u0627\u0646\u062f\u0627\u0632\u0647 \u0645\u0648\u0644\u06a9\u0648\u0644\u06cc \u0645\u062a\u0641\u0627\u0648\u062a \u0627\u0633\u062a \u06a9\u0647 \u0627\u0645\u06a9\u0627\u0646 \u062a\u0634\u062e\u06cc\u0635 \u062f\u0642\u06cc\u0642 (precise diagnosis) \u0631\u0627 \u0641\u0631\u0627\u0647\u0645 \u0645\u06cc\u200c\u0633\u0627\u0632\u062f. \u062a\u0634\u062e\u06cc\u0635 \u06a9\u0631\u0648\u0645\u0648\u0632\u0648\u0645 \u0641\u06cc\u0644\u0627\u062f\u0644\u0641\u06cc\u0627 (Philadelphia chromosome) \u0646\u0627\u0634\u06cc \u0627\u0632 \u062a\u0631\u0627\u0646\u0633\u200c\u0644\u0648\u06a9\u0627\u0633\u06cc\u0648\u0646 t(9;22)(q34;q11) \u0627\u0633\u062a.<\/span><\/p>\n

            \u0646\u06a9\u062a\u0647 \u0628\u0627\u0644\u06cc\u0646\u06cc:<\/span><\/p>\n

            \u0648\u062c\u0648\u062f \u0627\u06cc\u0646 \u0646\u0627\u0647\u0646\u062c\u0627\u0631\u06cc \u0698\u0646\u062a\u06cc\u06a9\u06cc \u06cc\u06a9\u06cc \u0627\u0632 \u0634\u0627\u062e\u0635\u200c\u0647\u0627\u06cc \u06a9\u0644\u0627\u0633\u06cc\u06a9 \u062f\u0631 \u0644\u0648\u0633\u0645\u06cc \u0645\u0632\u0645\u0646 \u0645\u06cc\u0644\u0648\u0626\u06cc\u062f\u06cc (CML) \u0628\u0648\u062f\u0647 \u0648 \u0645\u0628\u0646\u0627\u06cc \u062f\u0631\u0645\u0627\u0646 \u0647\u062f\u0641\u0645\u0646\u062f \u0628\u0627 \u0645\u0647\u0627\u0631\u06a9\u0646\u0646\u062f\u0647\u200c\u0647\u0627\u06cc \u062a\u06cc\u0631\u0648\u0632\u06cc\u0646 \u06a9\u06cc\u0646\u0627\u0632 (Tyrosine Kinase Inhibitors \u2013 TKIs) \u0627\u0633\u062a.<\/span><\/p>\n[\/vc_column_text][vc_separator color=”blue” border_width=”2″ css=””][\/vc_column][\/vc_row]\n\n\n

            \n \n
            \n \n
            \n
            \n \n\n
            <\/div>\n <\/div>\n
            \n \n\n
            <\/div>\n <\/div>\n
            \n \n\n
            <\/div>\n <\/div>\n
            \n \n\n
            <\/div>\n <\/div>\n
            \n \n\n
            <\/div>\n <\/div>\n <\/div>\n \n
            \n
            \n \n\n
            <\/div>\n <\/div>\n
            \n \n\n
            <\/div>\n <\/div>\n
            \n \n\n
            <\/div>\n <\/div>\n
            \n \n\n
            <\/div>\n <\/div>\n
            \n \n\n
            <\/div>\n <\/div>\n <\/div>\n<\/div>\n \n\n
            \n \u0627\u0645\u062a\u06cc\u0627\u0632 \u0634\u0645\u0627 \u0628\u0647 \u0627\u06cc\u0646 \u0635\u0641\u062d\u0647<\/span>\n <\/div>\n <\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"

            [vc_row][vc_column][vc_column_text css=””] \u0633\u0624\u0627\u0644 31 [\/vc_column_text][vc_column_text css=””] \u062a\u0635\u0648\u06cc\u0631 31 \u0622\u0633\u067e\u06cc\u0631\u0627\u0633\u06cc\u0648\u0646 \u0645\u063a\u0632 \u0627\u0633\u062a\u062e\u0648\u0627\u0646 \u0627\u0632 \u06cc\u06a9 \u067e\u0633\u0631 \u06f1\u06f6 \u0633\u0627\u0644\u0647 \u0631\u0627 \u0646\u0634\u0627\u0646 \u0645\u06cc\u200c\u062f\u0647\u062f \u06a9\u0647 \u0645\u0634\u062e\u0635 \u0634\u062f \u062f\u0686\u0627\u0631 \u0644\u0646\u0641\u0627\u062f\u0646\u0648\u067e\u0627\u062a\u06cc (lymphadenopathy) \u0634\u062f\u0647 \u0627\u0633\u062a. \u062a\u0634\u062e\u06cc\u0635 \u0686\u06cc\u0633\u062a\u061f [\/vc_column_text][vc_single_image image=”112372″ img_size=”full” css=””][vc_column_text css=””]\u067e\u0627\u0633\u062e \u0627\u06cc\u0646 \u062a\u0635\u0648\u06cc\u0631 \u0646\u0634\u0627\u0646\u200c\u062f\u0647\u0646\u062f\u0647 \u0645\u063a\u0632 \u0627\u0633\u062a\u062e\u0648\u0627\u0646\u06cc \u0627\u0633\u062a \u06a9\u0647 \u0627\u0632 \u0633\u0644\u0648\u0644\u200c\u0647\u0627\u06cc \u0628\u0644\u0627\u0633\u062a (blast cells) \u062a\u0634\u06a9\u06cc\u0644 \u0634\u062f\u0647 \u0627\u0633\u062a \u06a9\u0647 \u062f\u0627\u0631\u0627\u06cc \u0646\u0633\u0628\u062a \u0647\u0633\u062a\u0647 \u0628\u0647 \u0633\u06cc\u062a\u0648\u067e\u0644\u0627\u0633\u0645 …<\/p>\n","protected":false},"author":2,"featured_media":107687,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[113,110],"tags":[],"class_list":["post-112198","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-hematology-cases","category-case-study"],"yoast_head":"\n\u0622\u0632\u0645\u0648\u0646\u200c\u0647\u0627\u06cc \u0645\u0635\u0648\u0631 \u062a\u0634\u062e\u06cc\u0635\u06cc \u062f\u0631 \u0647\u0645\u0627\u062a\u0648\u0644\u0648\u0698\u06cc (\u0633\u0631\u06cc \u0686\u0647\u0627\u0631\u0645) - \u0645\u062c\u0644\u0647 \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/\" \/>\n<meta property=\"og:locale\" content=\"fa_IR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u0622\u0632\u0645\u0648\u0646\u200c\u0647\u0627\u06cc \u0645\u0635\u0648\u0631 \u062a\u0634\u062e\u06cc\u0635\u06cc \u062f\u0631 \u0647\u0645\u0627\u062a\u0648\u0644\u0648\u0698\u06cc (\u0633\u0631\u06cc \u0686\u0647\u0627\u0631\u0645)\" \/>\n<meta property=\"og:description\" content=\"[vc_row][vc_column][vc_column_text css=””] \u0633\u0624\u0627\u0644 31 [\/vc_column_text][vc_column_text css=””] \u062a\u0635\u0648\u06cc\u0631 31 \u0622\u0633\u067e\u06cc\u0631\u0627\u0633\u06cc\u0648\u0646 \u0645\u063a\u0632 \u0627\u0633\u062a\u062e\u0648\u0627\u0646 \u0627\u0632 \u06cc\u06a9 \u067e\u0633\u0631 \u06f1\u06f6 \u0633\u0627\u0644\u0647 \u0631\u0627 \u0646\u0634\u0627\u0646 \u0645\u06cc\u200c\u062f\u0647\u062f \u06a9\u0647 \u0645\u0634\u062e\u0635 \u0634\u062f \u062f\u0686\u0627\u0631 \u0644\u0646\u0641\u0627\u062f\u0646\u0648\u067e\u0627\u062a\u06cc (lymphadenopathy) \u0634\u062f\u0647 \u0627\u0633\u062a. \u062a\u0634\u062e\u06cc\u0635 \u0686\u06cc\u0633\u062a\u061f [\/vc_column_text][vc_single_image image=”112372″ img_size=”full” css=””][vc_column_text css=””]\u067e\u0627\u0633\u062e \u0627\u06cc\u0646 \u062a\u0635\u0648\u06cc\u0631 \u0646\u0634\u0627\u0646\u200c\u062f\u0647\u0646\u062f\u0647 \u0645\u063a\u0632 \u0627\u0633\u062a\u062e\u0648\u0627\u0646\u06cc \u0627\u0633\u062a \u06a9\u0647 \u0627\u0632 \u0633\u0644\u0648\u0644\u200c\u0647\u0627\u06cc \u0628\u0644\u0627\u0633\u062a (blast cells) \u062a\u0634\u06a9\u06cc\u0644 \u0634\u062f\u0647 \u0627\u0633\u062a \u06a9\u0647 \u062f\u0627\u0631\u0627\u06cc \u0646\u0633\u0628\u062a \u0647\u0633\u062a\u0647 \u0628\u0647 \u0633\u06cc\u062a\u0648\u067e\u0644\u0627\u0633\u0645 …\" \/>\n<meta property=\"og:url\" content=\"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/\" \/>\n<meta property=\"og:site_name\" content=\"\u0645\u062c\u0644\u0647 \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633\" \/>\n<meta property=\"article:published_time\" content=\"2026-06-17T12:07:01+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/medpip.com\/mag\/wp-content\/uploads\/2026\/05\/Hematology-case-study.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"720\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"\u06af\u0631\u0648\u0647 \u0645\u062d\u062a\u0648\u0627 \u0634\u0631\u06a9\u062a \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@poleideal\" \/>\n<meta name=\"twitter:site\" content=\"@poleideal\" \/>\n<meta name=\"twitter:label1\" content=\"\u0646\u0648\u0634\u062a\u0647\u200c\u0634\u062f\u0647 \u0628\u062f\u0633\u062a\" \/>\n\t<meta name=\"twitter:data1\" content=\"\u06af\u0631\u0648\u0647 \u0645\u062d\u062a\u0648\u0627 \u0634\u0631\u06a9\u062a \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633\" \/>\n\t<meta name=\"twitter:label2\" content=\"\u0632\u0645\u0627\u0646 \u062a\u0642\u0631\u06cc\u0628\u06cc \u0628\u0631\u0627\u06cc \u062e\u0648\u0627\u0646\u062f\u0646\" \/>\n\t<meta name=\"twitter:data2\" content=\"10 \u062f\u0642\u06cc\u0642\u0647\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/\"},\"author\":{\"name\":\"\u06af\u0631\u0648\u0647 \u0645\u062d\u062a\u0648\u0627 \u0634\u0631\u06a9\u062a \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633\",\"@id\":\"https:\/\/medpip.com\/mag\/#\/schema\/person\/9c6b8cb9468e0012fdd7747cd912d0be\"},\"headline\":\"\u0622\u0632\u0645\u0648\u0646\u200c\u0647\u0627\u06cc \u0645\u0635\u0648\u0631 \u062a\u0634\u062e\u06cc\u0635\u06cc \u062f\u0631 \u0647\u0645\u0627\u062a\u0648\u0644\u0648\u0698\u06cc (\u0633\u0631\u06cc \u0686\u0647\u0627\u0631\u0645)\",\"datePublished\":\"2026-06-17T12:07:01+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/\"},\"wordCount\":735,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/medpip.com\/mag\/#organization\"},\"image\":{\"@id\":\"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/medpip.com\/mag\/wp-content\/uploads\/2026\/05\/Hematology-case-study.jpg\",\"articleSection\":[\"\u0622\u0632\u0645\u0648\u0646 \u0647\u0627\u06cc \u0645\u0635\u0648\u0631 \u062a\u0634\u062e\u06cc\u0635\u06cc \u062f\u0631 \u0647\u0645\u0627\u062a\u0648\u0644\u0648\u0698\u06cc\",\"\u0645\u0637\u0627\u0644\u0639\u0647 \u0645\u0648\u0631\u062f\u06cc\"],\"inLanguage\":\"fa-IR\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/\",\"url\":\"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/\",\"name\":\"\u0622\u0632\u0645\u0648\u0646\u200c\u0647\u0627\u06cc \u0645\u0635\u0648\u0631 \u062a\u0634\u062e\u06cc\u0635\u06cc \u062f\u0631 \u0647\u0645\u0627\u062a\u0648\u0644\u0648\u0698\u06cc (\u0633\u0631\u06cc \u0686\u0647\u0627\u0631\u0645) - \u0645\u062c\u0644\u0647 \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633\",\"isPartOf\":{\"@id\":\"https:\/\/medpip.com\/mag\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/medpip.com\/mag\/wp-content\/uploads\/2026\/05\/Hematology-case-study.jpg\",\"datePublished\":\"2026-06-17T12:07:01+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/#breadcrumb\"},\"inLanguage\":\"fa-IR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"fa-IR\",\"@id\":\"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/#primaryimage\",\"url\":\"https:\/\/medpip.com\/mag\/wp-content\/uploads\/2026\/05\/Hematology-case-study.jpg\",\"contentUrl\":\"https:\/\/medpip.com\/mag\/wp-content\/uploads\/2026\/05\/Hematology-case-study.jpg\",\"width\":1280,\"height\":720,\"caption\":\"\u0645\u0637\u0627\u0644\u0639\u0647 \u0645\u0648\u0631\u062f\u06cc \u0647\u0645\u0627\u062a\u0648\u0644\u0648\u0698\u06cc\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/medpip.com\/mag\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"\u0622\u0632\u0645\u0648\u0646\u200c\u0647\u0627\u06cc \u0645\u0635\u0648\u0631 \u062a\u0634\u062e\u06cc\u0635\u06cc \u062f\u0631 \u0647\u0645\u0627\u062a\u0648\u0644\u0648\u0698\u06cc (\u0633\u0631\u06cc \u0686\u0647\u0627\u0631\u0645)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/medpip.com\/mag\/#website\",\"url\":\"https:\/\/medpip.com\/mag\/\",\"name\":\"\u0645\u062c\u0644\u0647 \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633\",\"description\":\"\u0645\u062c\u0644\u0647 \u062a\u062e\u0635\u0635\u06cc \u0639\u0644\u0648\u0645 \u0622\u0632\u0645\u0627\u06cc\u0634\u06af\u0627\u0647\u06cc\",\"publisher\":{\"@id\":\"https:\/\/medpip.com\/mag\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/medpip.com\/mag\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fa-IR\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/medpip.com\/mag\/#organization\",\"name\":\"\u0645\u062c\u0644\u0647 \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633\",\"url\":\"https:\/\/medpip.com\/mag\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fa-IR\",\"@id\":\"https:\/\/medpip.com\/mag\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/medpip.com\/mag\/wp-content\/uploads\/2020\/04\/pole-ideal-pars-mag-logo.png\",\"contentUrl\":\"https:\/\/medpip.com\/mag\/wp-content\/uploads\/2020\/04\/pole-ideal-pars-mag-logo.png\",\"width\":192,\"height\":303,\"caption\":\"\u0645\u062c\u0644\u0647 \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633\"},\"image\":{\"@id\":\"https:\/\/medpip.com\/mag\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/x.com\/poleideal\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/medpip.com\/mag\/#\/schema\/person\/9c6b8cb9468e0012fdd7747cd912d0be\",\"name\":\"\u06af\u0631\u0648\u0647 \u0645\u062d\u062a\u0648\u0627 \u0634\u0631\u06a9\u062a \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fa-IR\",\"@id\":\"https:\/\/medpip.com\/mag\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/ef0001933cfffcdffbaf0411052872eacde4ddbda7d86bfed31f6094e80627e5?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/ef0001933cfffcdffbaf0411052872eacde4ddbda7d86bfed31f6094e80627e5?s=96&d=mm&r=g\",\"caption\":\"\u06af\u0631\u0648\u0647 \u0645\u062d\u062a\u0648\u0627 \u0634\u0631\u06a9\u062a \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633\"},\"url\":\"https:\/\/medpip.com\/mag\/author\/medcontent98\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"\u0622\u0632\u0645\u0648\u0646\u200c\u0647\u0627\u06cc \u0645\u0635\u0648\u0631 \u062a\u0634\u062e\u06cc\u0635\u06cc \u062f\u0631 \u0647\u0645\u0627\u062a\u0648\u0644\u0648\u0698\u06cc (\u0633\u0631\u06cc \u0686\u0647\u0627\u0631\u0645) - \u0645\u062c\u0644\u0647 \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/","og_locale":"fa_IR","og_type":"article","og_title":"\u0622\u0632\u0645\u0648\u0646\u200c\u0647\u0627\u06cc \u0645\u0635\u0648\u0631 \u062a\u0634\u062e\u06cc\u0635\u06cc \u062f\u0631 \u0647\u0645\u0627\u062a\u0648\u0644\u0648\u0698\u06cc (\u0633\u0631\u06cc \u0686\u0647\u0627\u0631\u0645)","og_description":"[vc_row][vc_column][vc_column_text css=””] \u0633\u0624\u0627\u0644 31 [\/vc_column_text][vc_column_text css=””] \u062a\u0635\u0648\u06cc\u0631 31 \u0622\u0633\u067e\u06cc\u0631\u0627\u0633\u06cc\u0648\u0646 \u0645\u063a\u0632 \u0627\u0633\u062a\u062e\u0648\u0627\u0646 \u0627\u0632 \u06cc\u06a9 \u067e\u0633\u0631 \u06f1\u06f6 \u0633\u0627\u0644\u0647 \u0631\u0627 \u0646\u0634\u0627\u0646 \u0645\u06cc\u200c\u062f\u0647\u062f \u06a9\u0647 \u0645\u0634\u062e\u0635 \u0634\u062f \u062f\u0686\u0627\u0631 \u0644\u0646\u0641\u0627\u062f\u0646\u0648\u067e\u0627\u062a\u06cc (lymphadenopathy) \u0634\u062f\u0647 \u0627\u0633\u062a. \u062a\u0634\u062e\u06cc\u0635 \u0686\u06cc\u0633\u062a\u061f [\/vc_column_text][vc_single_image image=”112372″ img_size=”full” css=””][vc_column_text css=””]\u067e\u0627\u0633\u062e \u0627\u06cc\u0646 \u062a\u0635\u0648\u06cc\u0631 \u0646\u0634\u0627\u0646\u200c\u062f\u0647\u0646\u062f\u0647 \u0645\u063a\u0632 \u0627\u0633\u062a\u062e\u0648\u0627\u0646\u06cc \u0627\u0633\u062a \u06a9\u0647 \u0627\u0632 \u0633\u0644\u0648\u0644\u200c\u0647\u0627\u06cc \u0628\u0644\u0627\u0633\u062a (blast cells) \u062a\u0634\u06a9\u06cc\u0644 \u0634\u062f\u0647 \u0627\u0633\u062a \u06a9\u0647 \u062f\u0627\u0631\u0627\u06cc \u0646\u0633\u0628\u062a \u0647\u0633\u062a\u0647 \u0628\u0647 \u0633\u06cc\u062a\u0648\u067e\u0644\u0627\u0633\u0645 …","og_url":"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/","og_site_name":"\u0645\u062c\u0644\u0647 \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633","article_published_time":"2026-06-17T12:07:01+00:00","og_image":[{"width":1280,"height":720,"url":"https:\/\/medpip.com\/mag\/wp-content\/uploads\/2026\/05\/Hematology-case-study.jpg","type":"image\/jpeg"}],"author":"\u06af\u0631\u0648\u0647 \u0645\u062d\u062a\u0648\u0627 \u0634\u0631\u06a9\u062a \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633","twitter_card":"summary_large_image","twitter_creator":"@poleideal","twitter_site":"@poleideal","twitter_misc":{"\u0646\u0648\u0634\u062a\u0647\u200c\u0634\u062f\u0647 \u0628\u062f\u0633\u062a":"\u06af\u0631\u0648\u0647 \u0645\u062d\u062a\u0648\u0627 \u0634\u0631\u06a9\u062a \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633","\u0632\u0645\u0627\u0646 \u062a\u0642\u0631\u06cc\u0628\u06cc \u0628\u0631\u0627\u06cc \u062e\u0648\u0627\u0646\u062f\u0646":"10 \u062f\u0642\u06cc\u0642\u0647"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/#article","isPartOf":{"@id":"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/"},"author":{"name":"\u06af\u0631\u0648\u0647 \u0645\u062d\u062a\u0648\u0627 \u0634\u0631\u06a9\u062a \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633","@id":"https:\/\/medpip.com\/mag\/#\/schema\/person\/9c6b8cb9468e0012fdd7747cd912d0be"},"headline":"\u0622\u0632\u0645\u0648\u0646\u200c\u0647\u0627\u06cc \u0645\u0635\u0648\u0631 \u062a\u0634\u062e\u06cc\u0635\u06cc \u062f\u0631 \u0647\u0645\u0627\u062a\u0648\u0644\u0648\u0698\u06cc (\u0633\u0631\u06cc \u0686\u0647\u0627\u0631\u0645)","datePublished":"2026-06-17T12:07:01+00:00","mainEntityOfPage":{"@id":"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/"},"wordCount":735,"commentCount":0,"publisher":{"@id":"https:\/\/medpip.com\/mag\/#organization"},"image":{"@id":"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/#primaryimage"},"thumbnailUrl":"https:\/\/medpip.com\/mag\/wp-content\/uploads\/2026\/05\/Hematology-case-study.jpg","articleSection":["\u0622\u0632\u0645\u0648\u0646 \u0647\u0627\u06cc \u0645\u0635\u0648\u0631 \u062a\u0634\u062e\u06cc\u0635\u06cc \u062f\u0631 \u0647\u0645\u0627\u062a\u0648\u0644\u0648\u0698\u06cc","\u0645\u0637\u0627\u0644\u0639\u0647 \u0645\u0648\u0631\u062f\u06cc"],"inLanguage":"fa-IR","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/medpip.com\/mag\/hematology-case-studies-4\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/","url":"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/","name":"\u0622\u0632\u0645\u0648\u0646\u200c\u0647\u0627\u06cc \u0645\u0635\u0648\u0631 \u062a\u0634\u062e\u06cc\u0635\u06cc \u062f\u0631 \u0647\u0645\u0627\u062a\u0648\u0644\u0648\u0698\u06cc (\u0633\u0631\u06cc \u0686\u0647\u0627\u0631\u0645) - \u0645\u062c\u0644\u0647 \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633","isPartOf":{"@id":"https:\/\/medpip.com\/mag\/#website"},"primaryImageOfPage":{"@id":"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/#primaryimage"},"image":{"@id":"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/#primaryimage"},"thumbnailUrl":"https:\/\/medpip.com\/mag\/wp-content\/uploads\/2026\/05\/Hematology-case-study.jpg","datePublished":"2026-06-17T12:07:01+00:00","breadcrumb":{"@id":"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/#breadcrumb"},"inLanguage":"fa-IR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/medpip.com\/mag\/hematology-case-studies-4\/"]}]},{"@type":"ImageObject","inLanguage":"fa-IR","@id":"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/#primaryimage","url":"https:\/\/medpip.com\/mag\/wp-content\/uploads\/2026\/05\/Hematology-case-study.jpg","contentUrl":"https:\/\/medpip.com\/mag\/wp-content\/uploads\/2026\/05\/Hematology-case-study.jpg","width":1280,"height":720,"caption":"\u0645\u0637\u0627\u0644\u0639\u0647 \u0645\u0648\u0631\u062f\u06cc \u0647\u0645\u0627\u062a\u0648\u0644\u0648\u0698\u06cc"},{"@type":"BreadcrumbList","@id":"https:\/\/medpip.com\/mag\/hematology-case-studies-4\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/medpip.com\/mag\/"},{"@type":"ListItem","position":2,"name":"\u0622\u0632\u0645\u0648\u0646\u200c\u0647\u0627\u06cc \u0645\u0635\u0648\u0631 \u062a\u0634\u062e\u06cc\u0635\u06cc \u062f\u0631 \u0647\u0645\u0627\u062a\u0648\u0644\u0648\u0698\u06cc (\u0633\u0631\u06cc \u0686\u0647\u0627\u0631\u0645)"}]},{"@type":"WebSite","@id":"https:\/\/medpip.com\/mag\/#website","url":"https:\/\/medpip.com\/mag\/","name":"\u0645\u062c\u0644\u0647 \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633","description":"\u0645\u062c\u0644\u0647 \u062a\u062e\u0635\u0635\u06cc \u0639\u0644\u0648\u0645 \u0622\u0632\u0645\u0627\u06cc\u0634\u06af\u0627\u0647\u06cc","publisher":{"@id":"https:\/\/medpip.com\/mag\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/medpip.com\/mag\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fa-IR"},{"@type":"Organization","@id":"https:\/\/medpip.com\/mag\/#organization","name":"\u0645\u062c\u0644\u0647 \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633","url":"https:\/\/medpip.com\/mag\/","logo":{"@type":"ImageObject","inLanguage":"fa-IR","@id":"https:\/\/medpip.com\/mag\/#\/schema\/logo\/image\/","url":"https:\/\/medpip.com\/mag\/wp-content\/uploads\/2020\/04\/pole-ideal-pars-mag-logo.png","contentUrl":"https:\/\/medpip.com\/mag\/wp-content\/uploads\/2020\/04\/pole-ideal-pars-mag-logo.png","width":192,"height":303,"caption":"\u0645\u062c\u0644\u0647 \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633"},"image":{"@id":"https:\/\/medpip.com\/mag\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/x.com\/poleideal"]},{"@type":"Person","@id":"https:\/\/medpip.com\/mag\/#\/schema\/person\/9c6b8cb9468e0012fdd7747cd912d0be","name":"\u06af\u0631\u0648\u0647 \u0645\u062d\u062a\u0648\u0627 \u0634\u0631\u06a9\u062a \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633","image":{"@type":"ImageObject","inLanguage":"fa-IR","@id":"https:\/\/medpip.com\/mag\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/ef0001933cfffcdffbaf0411052872eacde4ddbda7d86bfed31f6094e80627e5?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/ef0001933cfffcdffbaf0411052872eacde4ddbda7d86bfed31f6094e80627e5?s=96&d=mm&r=g","caption":"\u06af\u0631\u0648\u0647 \u0645\u062d\u062a\u0648\u0627 \u0634\u0631\u06a9\u062a \u067e\u0644 \u0627\u06cc\u062f\u0647\u200c\u0622\u0644 \u067e\u0627\u0631\u0633"},"url":"https:\/\/medpip.com\/mag\/author\/medcontent98\/"}]}},"_links":{"self":[{"href":"https:\/\/medpip.com\/mag\/wp-json\/wp\/v2\/posts\/112198","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medpip.com\/mag\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medpip.com\/mag\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medpip.com\/mag\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/medpip.com\/mag\/wp-json\/wp\/v2\/comments?post=112198"}],"version-history":[{"count":4,"href":"https:\/\/medpip.com\/mag\/wp-json\/wp\/v2\/posts\/112198\/revisions"}],"predecessor-version":[{"id":112635,"href":"https:\/\/medpip.com\/mag\/wp-json\/wp\/v2\/posts\/112198\/revisions\/112635"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medpip.com\/mag\/wp-json\/wp\/v2\/media\/107687"}],"wp:attachment":[{"href":"https:\/\/medpip.com\/mag\/wp-json\/wp\/v2\/media?parent=112198"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medpip.com\/mag\/wp-json\/wp\/v2\/categories?post=112198"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medpip.com\/mag\/wp-json\/wp\/v2\/tags?post=112198"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}